Here is how I reached the solution with my elementary knowledge 😛

First,

we can find that the red coloured digits must be zero as they are brought down from the top row.



The red digit in the quotient is zero because when $***×\color{red}*=**$, where the first digit is non-zero (clearly, in this case), the red digit must be a zero, otherwise the result will be a three digit number.

Now consider,

Clearly $d\neq0$ and so is $c$. As $a\cdot b=..c\neq0$, none of $a$ and $b$ is equal to zero. Thus in order to get the product $a\cdot e=…0$, one of them must be $5$ with other being an even number.

Now…

… assume $e=5$. In order to get $**a×e=d000$, ‘$a$‘ has to be zero. (Eg:- consider $200×5=1000$, $400×5=2000,$ etc.), but then it’s a contradiction. Therefore from the previous argument, $a$ must be $5$. Also then, $e$ is an even number but we can reduce the possiblity to $\{4,8\}$, because when multiplied, there should be a number with last two (three, actually) digits being $0$.

Then…

… since $c\neq0$, it should be $5$. So $d$ also becomes $5$. Then we have $**5×e=5000$. We see that $5000=2^3×5^4$. We need to fill the numbers in $\text{_ _} 5 × \text_ =5000$, where the one digit number is confirmed to be $4$ or $8$. If it is $4$ the other number in the product should be a 4-digit number, which leads to a contradiction. Thus we can easily find that it is $8$ as in $625×8=5000$.

Now we can easily deduce that..

… the other digits in the quotient are $1$s because the every product remaining (i.e. $625×*$) results in a 3-digit number. So we can see that $b$ should be a $1$, giving $625$ (where the last digit was $c$ previously) and the prior number $630$. From there working backwards we can find all the missing numbers.

Hope I made it clear.